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Using two separate drugs to lose weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people that go through it you need to err on the side of caution and allow FDA do its job and demand some study be done so that the public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to make money and that they would say everything to keep people on his or her medications. Researchers found that participants taking this drug to get a year, dropped excess weight within 4 weeks and have kept the extra weight off throughout the 56 weeks of the study. Contrave is often a combination in the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which can be made up of several active ingredient, that might make them far better and safer. Combo-pilling may be the newest fad or better yet the newest into the future under scrutiny and thus it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular is the fact that since right now there aren't any long term prescription weight loss supplements that have been authorized by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise blood pressure and heartrate, and shouldn't be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must 't be used in patients with uncontrolled high blood pressure level, in addition to by you aren't heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients which has a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients on the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. 
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