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Using two separate drugs to lose weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight-loss and the people who go through it you should err on the side of caution and let the FDA do its job and demand some study be done in order that the public knows the side effects and perils associated with the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on their medications. Researchers found that participants using this drug for the year, dropped excess weight within four weeks and have kept the load off through the 56 weeks with the study. Contrave can be a combination from the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, which may make them far better and safer. Combo-pilling is the newest fad or in addition to this the newest into the future under scrutiny and for that reason it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills has become popular could be the fact that as of right now there aren't long term prescription weightloss pills that have been licensed by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug may also raise blood pressure and heartrate, and mustn't be used in those with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not used in patients with uncontrolled high blood pressure, as well as by you are not heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients for the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking. Most of the combinations which can be used to enhance weight-loss involve an amphetamine and an antidepressant. Phentermine and Prozac are a popular combination that were around for a while, and although it has been around my own mail to truly combine the two and try to get FDA approval to advertise it as a fat loss pill. Right there should raise some warning flags if the greedy pharmaceutical companies should not be involved in combining medications and selling them something should be wrong using the combination. In fairness there's one weight loss combination pill that's in front of the FDA now Contrave?which couples naltrexone, employed to treat alcohol and substance abuse, with the antidepressant bupropion (Wellbutrin, Zyban) it's been given the go ahead to move forward by an FDA advisory committee, but by yet hasn't been approved.